Renewa iLift

Niacinamide Serum: Benefits, How to Use It & What to Pair It With

Updated · 5 min read · By the Renewa Skin team

Niacinamide, a form of vitamin B3, is one of the most widely used skincare ingredients — and for good reason. It's gentle, suits most skin types, and plays well with almost everything else in your routine. Here's what it does and how to use it.

What does niacinamide do?

Niacinamide is well studied in cosmetic dermatology. It is used to support a healthy skin barrier, help skin hold on to moisture, and improve the look of uneven tone, redness, and enlarged pores. Over time, many people find it helps their skin look smoother and more even.

  • Supports the skin barrier and hydration
  • Helps even out the look of skin tone and dark spots
  • Helps minimize the appearance of pores
  • Can make skin look smoother and more refined with regular use

Who is it for?

Niacinamide is suitable for most skin types, including sensitive and mature skin. Concentrations of 2–5% are common and well tolerated; higher strengths are available but can occasionally cause irritation in sensitive skin. If you're new to it, start once a day.

How to use a niacinamide serum

Apply a few drops to clean skin, before your moisturizer. You can use it morning, evening, or both. In the morning, always finish with sunscreen.

What to pair it with

One of niacinamide's biggest strengths is compatibility:

  • Retinol: niacinamide is often used alongside retinol to help offset dryness
  • Vitamin C: modern formulas can be used together; if your skin is sensitive, use vitamin C in the morning and niacinamide at night
  • Hyaluronic acid: pairs well for extra hydration
  • Sunscreen: essential in any routine targeting tone and fine lines

Using niacinamide with an at-home device

Serums help devices glide smoothly over the skin, and sonic vibration provides a gentle micro-massage that helps work serum in. The Renewa iLift Best Value bundle includes three Swiss niacinamide serums for exactly this purpose: apply a thin layer, then glide the device along your smile and marionette lines for about 5 minutes.

Frequently asked questions

Can I use niacinamide every day?

Yes. Niacinamide is gentle enough for daily use, once or twice a day, for most skin types.

Does niacinamide help with wrinkles?

Niacinamide supports the skin barrier and can make skin look smoother and more even with regular use. For fine lines, it works best as part of a routine that includes sunscreen and, if tolerated, a retinoid.

Related guides